Ganglioside GM(1a) on the cell surface is involved in the infection by human rotavirus KUN and MO strains.

@article{Guo1999GangliosideGO,
  title={Ganglioside GM(1a) on the cell surface is involved in the infection by human rotavirus KUN and MO strains.},
  author={Chao-tan Guo and Osamu Nakagomi and Mayumi Mochizuki and Hitoshi Ishida and Makoto Kiso and Yasutaka Ohta and Toshio Suzuki and Daisei Miyamoto and Kazuya I-P Jwa Hidari and Yasuo Suzuki},
  journal={Journal of biochemistry},
  year={1999},
  volume={126 4},
  pages={
          683-8
        }
}
Rotavirus is the most common cause of severe gastroenteritis in infants and children worldwide. The cell attachment of most animal rotaviruses, which belong to the neuraminidase-sensitive strains, requires sialic acid residues on the host cell membranes. On the other hand, most human rotaviruses are classified as neuraminidase-insensitive strains. The involvement of gangliosides on the host cell surface in human rotavirus infection was investigated by immunostaining analysis of target cells… CONTINUE READING

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