Ganglioside GD3: structure, cellular distribution, and possible function

  title={Ganglioside GD3: structure, cellular distribution, and possible function},
  author={Thomas N. Seyfrieda and Robert K. Yu},
  journal={Molecular and Cellular Biochemistry},
Insight on the function of gangliosides. can emerge from knowledge of their cellular distribution. In this paper we review the structure of ganglioside GD3 and recent information on its cellular distribution. GD3 appears to be enriched in a variety of neural cell types including: reactive glia, gliomas, undifferentiated neurons, Muller glia, and oligodendroglia. Because each of these cell types share an enhanced permeability to ions and metabolites or possess properties associated with enhanced… CONTINUE READING