Ganglionic nAChRs and high-affinity nicotinic binding sites are not equivalent.

Abstract

High-affinity (Kd approximately equal to 10 nM) binding sites for nicotine and acetylcholine (ACh) have recently been identified in vertebrate brain. It has been suggested that these sites are desensitized ganglionic (C6) nicotinic acetylcholine receptors (nAChRs). We have tested the pheochromocytoma cell line PC12, which is known to contain well-expressed… (More)

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Cite this paper

@article{Kemp1986GanglionicNA, title={Ganglionic nAChRs and high-affinity nicotinic binding sites are not equivalent.}, author={Garreth Kemp and Barbara J Morley}, journal={FEBS letters}, year={1986}, volume={205 2}, pages={265-8} }