Gammahydroxybutyrate: An endogenous regulator of energy metabolism

@article{Mamelak1990GammahydroxybutyrateAE,
  title={Gammahydroxybutyrate: An endogenous regulator of energy metabolism},
  author={M. Mamelak},
  journal={Neuroscience & Biobehavioral Reviews},
  year={1990},
  volume={13},
  pages={187-198}
}
  • M. Mamelak
  • Published 1990
  • Biology, Medicine
  • Neuroscience & Biobehavioral Reviews
  • Gammahydroxybutyrate is a naturally occurring metabolite of many mammalian tissues. Although its administration produces a wide range of pharmacological effects, its normal function has never been clearly defined. GHB can induce NREM and REM sleep, anaesthesia, hypothermia, and a trance-like state which has been considered a model for petit mal epilepsy. It markedly increases brain dopamine levels. It has been touted as a central neurotransmitter or neuromodulator, and high affinity brain… CONTINUE READING
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