Gammaherpesvirus-Driven Plasma Cell Differentiation Regulates Virus Reactivation from Latently Infected B Lymphocytes

@inproceedings{Liang2009GammaherpesvirusDrivenPC,
  title={Gammaherpesvirus-Driven Plasma Cell Differentiation Regulates Virus Reactivation from Latently Infected B Lymphocytes},
  author={Xiaozhen Liang and Christopher M P Collins and Justin B. Mendel and Neal N. Iwakoshi and Samuel H Speck},
  booktitle={PLoS pathogens},
  year={2009}
}
Gammaherpesviruses chronically infect their host and are tightly associated with the development of lymphoproliferative diseases and lymphomas, as well as several other types of cancer. Mechanisms involved in maintaining chronic gammaherpesvirus infections are poorly understood and, in particular, little is known about the mechanisms involved in controlling gammaherpesvirus reactivation from latently infected B cells in vivo. Recent evidence has linked plasma cell differentiation with… CONTINUE READING

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