Gamma-ray-irradiated red blood cells stored in mannitol-adenine-phosphate medium: rheological evaluation and susceptibility to oxidative stress.

@article{Cicha2000GammarayirradiatedRB,
  title={Gamma-ray-irradiated red blood cells stored in mannitol-adenine-phosphate medium: rheological evaluation and susceptibility to oxidative stress.},
  author={Iwona Cicha and Yoko Suzuki and Norihiko Tateishi and Makoto Shiba and Masato Muraoka and Kenji Tadokoro and Nobuji Maeda},
  journal={Vox sanguinis},
  year={2000},
  volume={79 2},
  pages={75-82}
}
BACKGROUND AND OBJECTIVES To evaluate the rheological properties and the oxidative susceptibility of gamma-ray-irradiated red blood cells (RBCs). MATERIALS AND METHODS RBCs in mannitol-adenine-phosphate (MAP) medium were irradiated with 35 Gy and stored at 4 degrees C for 4 weeks. The deformability of the RBCs was examined under shear flow in relation to the morphological and biochemical changes. The RBCs were further exposed to 1 mM FeSO(4) and 5 mM ascorbate to examine the oxidative… CONTINUE READING

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