Gamma knife radiosurgery in the management of malignant melanoma brain metastases.

  title={Gamma knife radiosurgery in the management of malignant melanoma brain metastases.},
  author={David Mathieu and Douglas Kondziolka and Patrick B. Cooper and J C Flickinger and Ajay Niranjan and Sanjiv S. Agarwala and John Munn Kirkwood and L D Lunsford},
  volume={60 3},
  pages={471-81; discussion 481-2}
OBJECTIVE Radiosurgery is increasingly used to manage malignant melanoma brain metastases. We reviewed our series of patients who underwent radiosurgery for melanoma brain metastases to assess clinical outcomes and identify prognostic factors for survival and cerebral disease control. METHODS Two hundred forty-four patients had radiosurgery for the management of 754 metastatic tumors. A mean of 2.6 tumors were irradiated per procedure. The median tumor volume was 4.4 cm3. The median margin… CONTINUE READING
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