Gamma interferon augments Fc gamma receptor-mediated dengue virus infection of human monocytic cells.

@article{Kontny1988GammaIA,
  title={Gamma interferon augments Fc gamma receptor-mediated dengue virus infection of human monocytic cells.},
  author={Udo Kontny and Ichiro Kurane and Francis A. Ennis},
  journal={Journal of virology},
  year={1988},
  volume={62 11},
  pages={3928-33}
}
It has been reported that anti-dengue antibodies at subneutralizing concentrations augment dengue virus infection of monocytic cells. This is due to the increased uptake of dengue virus in the form of virus-antibody complexes by cells via Fc gamma receptors. We analyzed the effects of recombinant human gamma interferon (rIFN-gamma) on dengue virus infection of human monocytic cells. U937 cells, a human monocytic cell line, were infected with dengue virus in the form of virus-antibody complexes… CONTINUE READING
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