Gamma-hydroxybutyric acid versus clomethiazole for the treatment of alcohol withdrawal syndrome in a medical intensive care unit: an open, single-center randomized study.

@article{Elsing2009GammahydroxybutyricAV,
  title={Gamma-hydroxybutyric acid versus clomethiazole for the treatment of alcohol withdrawal syndrome in a medical intensive care unit: an open, single-center randomized study.},
  author={Christoph Elsing and Wolfgang Stremmel and Uwe Grenda and Thomas Herrmann},
  journal={The American journal of drug and alcohol abuse},
  year={2009},
  volume={35 3},
  pages={189-92}
}
BACKGROUND Clomethiazole (CLO) has been shown to be effective in treating alcohol withdrawal syndrome (AWS). Gamma-Hydroxybutyric acid (GHB) has also been introduced in the treatment of alcoholic patients and is effective in surgical intensive care unit (ICU) patients in preventing and treating AWS. There are no comparative studies between CLO and GHB in a medical ICU setting. METHODS Twenty-six alcoholic patients with severe AWS and concomitant medical diseases were randomally enrolled in… CONTINUE READING