Gamma-hydroxybutyric acid (GHB) in the treatment of alcohol withdrawal syndrome: a randomized comparative study versus benzodiazepine.

@article{Addolorato1999GammahydroxybutyricA,
  title={Gamma-hydroxybutyric acid (GHB) in the treatment of alcohol withdrawal syndrome: a randomized comparative study versus benzodiazepine.},
  author={Giovanni Addolorato and Genoveffa Balducci and Esmeralda Capristo and Maria Luisa Attilia and Franco Taggi and Giovanni Battista Gasbarrini and Mauro Ceccanti},
  journal={Alcoholism, clinical and experimental research},
  year={1999},
  volume={23 10},
  pages={1596-604}
}
BACKGROUND Benzodiazepine has been shown to be one of the most effective class of drugs in the management of alcohol withdrawal syndrome (AWS). Gamma-hydroxybutyric acid (GHB) has recently been introduced in the treatment of alcohol problems, including AWS. At present there are no comparative studies between benzodiazepines and GHB in AWS treatment. The aim of the present randomized, controlled, single-blind study was to evaluate the efficacy and safety of GHB compared with diazepam in the… CONTINUE READING
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