Gamma-hydroxybutyrate (GHB) for treatment of alcohol withdrawal and prevention of relapses.

@article{Leone2010GammahydroxybutyrateF,
  title={Gamma-hydroxybutyrate (GHB) for treatment of alcohol withdrawal and prevention of relapses.},
  author={M A Leone and Federica Daniela Vigna-Taglianti and Giancarlo Avanzi and Romeo Brambilla and F Francesco Faggiano},
  journal={The Cochrane database of systematic reviews},
  year={2010},
  volume={2},
  pages={
          CD006266
        }
}
BACKGROUND Chronic excessive alcohol consumption may lead to dependence, and to alcohol withdrawal syndrome (AWS) in case of abrupt drinking cessation. Gamma-hydroxybutyric acid (GHB) can prevent and suppress withdrawal symptoms, and improve the medium-term abstinence rate. A clear balance between effectiveness and harmfulness has not been yet established. OBJECTIVES To evaluate the efficacy and safety of GHB for treatment of AWS and prevention of relapse SEARCH STRATEGY We searched… CONTINUE READING
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