Gamma-hydroxybutyrate (GHB) induces cognitive deficits and affects GABAB receptors and IGF-1 receptors in male rats.

@article{Johansson2014GammahydroxybutyrateI,
  title={Gamma-hydroxybutyrate (GHB) induces cognitive deficits and affects GABAB receptors and IGF-1 receptors in male rats.},
  author={Jenny G Johansson and Alfhild Gr{\"o}nbladh and Mathias Hallberg},
  journal={Behavioural brain research},
  year={2014},
  volume={269},
  pages={164-74}
}
In recent years, the abuse of the club drug gamma-hydroxybutyrate (GHB) has become increasingly popular among adolescents. The drug induces euphoria but can also result in sedation, anaesthesia as well as short-term amnesia. In addition, the abuse of GHB causes cognitive impairments and the mechanism by which GHB induces these impairments is not clarified. The present study investigates the impact of GHB treatment on spatial learning and memory using a water maze (WM) test in rats. Furthermore… CONTINUE READING