Gamma heavy-chain disease: defining the spectrum of associated lymphoproliferative disorders through analysis of 13 cases.

@article{Bieliauskas2012GammaHD,
  title={Gamma heavy-chain disease: defining the spectrum of associated lymphoproliferative disorders through analysis of 13 cases.},
  author={Shannon Bieliauskas and Raymond R. Tubbs and Chris M Bacon and Camellia Eshoa and Kathryn Foucar and Sarah E. Gibson and Steven H. Kroft and Aliyah R. Sohani and Steven H Swerdlow and James R Cook},
  journal={The American journal of surgical pathology},
  year={2012},
  volume={36 4},
  pages={534-43}
}
Gamma heavy-chain disease (gHCD) is defined as a lymphoplasmacytic neoplasm that produces an abnormally truncated immunoglobulin gamma heavy-chain protein that lacks associated light chains. There is scant information in the literature regarding the morphologic findings in this rare disorder, but cases have often been reported to resemble lymphoplasmacytic lymphoma (LPL). To clarify the spectrum of lymphoproliferative disorders that may be associated with gHCD, this study reports the clinical… CONTINUE READING
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