Gamma glutamyl transpeptidase in safrole-induced, presumptive premalignant mouse hepatocytes.

Abstract

A histochemical procedure was used to determine the presence of gamma-glutamyl transpeptidase (GGT) in the livers of control, regenerating and carcinogen-treated mice. Young Balb/c mice were fed safrole, a naturally occurring hepatocarcinogen (0.4% w/w), for one year. Ten mice from control and ten mice from the safrole-treated group were killed at 4, 8, 16… (More)

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