Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.

@article{Chikhi1999GammaglutamylTG,
  title={Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.},
  author={Nassim Chikhi and Nathalie Holic and Georges Guellaen and Yannick Laperche},
  journal={Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology},
  year={1999},
  volume={122 4},
  pages={367-80}
}
Gamma-glutamyl transpeptidase (GGT) is an enzyme located at the external surface of epithelial cells. It initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. GGT expression, highly sensitive to oxidative stress, is a part of the cell antioxidant defense… CONTINUE READING