Gamma globulin levels predict type 2 diabetes in the Pima Indian population.

@article{Lindsay2001GammaGL,
  title={Gamma globulin levels predict type 2 diabetes in the Pima Indian population.},
  author={Robert S. Lindsay and Jonathan Krakoff and Robert L Hanson and Peter H. Bennett and William C. Knowler},
  journal={Diabetes},
  year={2001},
  volume={50 7},
  pages={1598-603}
}
It has been proposed that inflammation or infection may contribute to the development of type 2 diabetes. We examined whether serum gamma globulin, a nonspecific measure of the humoral immune system, predicted changes in glucose tolerance in 2,530 members of the Pima Indian population, a group with a marked predisposition to type 2 diabetes. Cross-sectionally, gamma globulin was positively related to age (r = 0.08, P < 0.0005), BMI (r = 0.09; P < 0.0001), and female sex (P < 0.0001). Gamma… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

An immune origin of type 2 diabetes?

Diabetologia • 2005
View 2 Excerpts
Highly Influenced

Importance of inflammatory markers and IL-6 for diagnosis and follow up of patients with type 2 diabetes mellitus.

Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina • 2017
View 1 Excerpt

Endurance exercise alters cellular immune status and resistin concentrations in men suffering from non-insulin-dependent type 2 diabetes.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association • 2013

References

Publications referenced by this paper.
Showing 1-10 of 27 references

Estimation of alterations of serum gamma globulin by a turbidimetric technique.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine • 1947
View 3 Excerpts
Highly Influenced

Function of C-reactive protein

TW Du Clos
Ann Med • 2000
View 1 Excerpt

An overview of American Indian demographic history

N Shoemaker
University of New Mexico Press, • 1999
View 1 Excerpt

Similar Papers

Loading similar papers…