Gamma delta T cells of human early pregnancy decidua: evidence for local proliferation, phenotypic heterogeneity, and extrathymic differentiation.

@article{MinchevaNilsson1997GammaDT,
  title={Gamma delta T cells of human early pregnancy decidua: evidence for local proliferation, phenotypic heterogeneity, and extrathymic differentiation.},
  author={Lucia Mincheva-Nilsson and M. Kling and Sten G. Hammarstr{\"o}m and Olga S. Nagaeva and Kerstin Sundqvist and Mats Hammarstr{\"o}m and Vladimir Baranov},
  journal={Journal of immunology},
  year={1997},
  volume={159 7},
  pages={
          3266-77
        }
}
The uterine mucosa in pregnancy, the decidua, allows placenta formation and survival of the fetus despite the fact that it is semiallogeneic. Decidua contains large numbers of lymphocytes, of which CD56+ cells dominate, followed by T cells expressing either alpha beta or gamma delta TCR. We have investigated the developmental relationship between the CD56- and TCR gamma delta-expressing cells in early pregnancy decidua using dual labeling immunoelectron microscopy, immunoflow cytometry, and… CONTINUE READING

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