Gamma delta T cell receptor variable region usage during the development of experimental allergic encephalomyelitis.

@article{Olive1995GammaDT,
  title={Gamma delta T cell receptor variable region usage during the development of experimental allergic encephalomyelitis.},
  author={Colleen Olive},
  journal={Journal of neuroimmunology},
  year={1995},
  volume={62 1},
  pages={1-7}
}
The molecular diversity of gamma delta T cells has not previously been investigated in experimental allergic encephalomyelitis (EAE). This study characterised the gamma delta T cell receptor (TCR) variable (V) region repertoires of T cells infiltrating the brains of EAE mice during development of the disease. TCR gamma- and delta-specific cDNAs were synthesised from total RNA prepared from brain samples and transcription of rearranged V genes was assessed by polymerase chain reaction… CONTINUE READING