Gamma delta T cell homeostasis is controlled by IL-7 and IL-15 together with subset-specific factors.

@article{Baccala2005GammaDT,
  title={Gamma delta T cell homeostasis is controlled by IL-7 and IL-15 together with subset-specific factors.},
  author={Roberto Baccala and Deborah A. Witherden and Rosana Gonzalez-Quintial and Wolfgang Dummer and Charles D. Surh and Wendy L. Havran and Argyrios N. Theofilopoulos},
  journal={Journal of immunology},
  year={2005},
  volume={174 8},
  pages={4606-12}
}
Among T cell subsets, gamma delta T cells uniquely display an Ag receptor-based tissue distribution, but what defines their preferential homing and homeostasis is unknown. To address this question, we studied the resources that control gamma delta T cell homeostasis in secondary lymphoid organs. We found that gamma delta and alpha beta T cells are controlled by partially overlapping resources, because acute homeostatic proliferation of gamma delta T cells was inhibited by an intact alpha beta T… CONTINUE READING

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