Gamma-delta (γδ) T cells: friend or foe in cancer development?

  title={Gamma-delta (γδ) T cells: friend or foe in cancer development?},
  author={Yijing Zhao and Chao-Shi Niu and Jiuwei Cui},
  booktitle={Journal of Translational Medicine},
γδ T cells are a distinct subgroup of T cells containing T cell receptors (TCRs) γ and TCR δ chains with diverse structural and functional heterogeneity. As a bridge between the innate and adaptive immune systems, γδ T cells participate in various immune responses during cancer progression. Because of their direct/indirect antitumor cytotoxicity and strong cytokine production ability, the use of γδ T cells in cancer immunotherapy has received a lot of attention over the past decade. Despite the… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS
6 Citations
117 References
Similar Papers


Publications referenced by this paper.
Showing 1-10 of 117 references

a new player on the cell therapy field? Mol Ther

  • GM Siegers, Lamb LS Jr. Cytotoxic, regulatory properties of circulating Vdelta1 gammadelta T cells
  • 2014;22:1416–22. Page 11 of 13 Zhao et al. J…
  • 2018
1 Excerpt

Similar Papers

Loading similar papers…