Gamma-delta (γδ) T cells: friend or foe in cancer development?

@inproceedings{Zhao2017GammadeltaT,
  title={Gamma-delta (γδ) T cells: friend or foe in cancer development?},
  author={Yijing Zhao and Chao-Shi Niu and Jiuwei Cui},
  booktitle={Journal of Translational Medicine},
  year={2017}
}
γδ T cells are a distinct subgroup of T cells containing T cell receptors (TCRs) γ and TCR δ chains with diverse structural and functional heterogeneity. As a bridge between the innate and adaptive immune systems, γδ T cells participate in various immune responses during cancer progression. Because of their direct/indirect antitumor cytotoxicity and strong cytokine production ability, the use of γδ T cells in cancer immunotherapy has received a lot of attention over the past decade. Despite the… CONTINUE READING
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