Gamma-aminobutyric acid (GABA) receptor rho (GABRR) polymorphisms and risk for essential tremor

@article{GarcaMartn2010GammaaminobutyricA,
  title={Gamma-aminobutyric acid (GABA) receptor rho (GABRR) polymorphisms and risk for essential tremor},
  author={Elena Garc{\'i}a-Mart{\'i}n and Carmen Martı́nez and Hortensia Alonso-Navarro and Juli{\'a}n Benito-Le{\'o}n and Oswaldo Lorenzo-Betancor and Pau P{\'a}stor and Inmaculada Puertas and Lluisa Rubio and Tom{\'a}s L{\'o}pez-Alburquerque and Jos{\'e} A. G. Ag{\'u}ndez and F{\'e}lix Javier Jim{\'e}nez-Jim{\'e}nez},
  journal={Journal of Neurology},
  year={2010},
  volume={258},
  pages={203-211}
}
Some clinical and experimental data suggest a possible role of gamma-aminobutyrate (GABA)-ergic mechanisms in the pathophysiology of essential tremor (ET), such as the improvement of ET with some GABAergic drugs and the development of an experimental model of ET in GABA A receptor alpha-1 knockout mice (postural and kinetic tremor and motor incoordination similar to human ET). To investigate the possible association between the GABA receptor subtype rho1, rho2, and rho3 (GABRR1, GABRR2, and… Expand
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  • Tremor and other hyperkinetic movements
  • 2014
TLDR
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TLDR
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