Gamma-aminobutyric acid, a potential tumor suppressor for small airway-derived lung adenocarcinoma

@article{Schuller2008GammaaminobutyricAA,
  title={Gamma-aminobutyric acid, a potential tumor suppressor for small airway-derived lung adenocarcinoma},
  author={Hildegard M. Schuller and Hussein A. N. Al-Wadei and Mourad Majidi},
  journal={Carcinogenesis},
  year={2008},
  volume={29},
  pages={1979 - 1985}
}
Pulmonary adenocarcinoma (PAC) is the leading type of lung cancer in smokers and non-smokers that arises in most cases from small airway epithelial cells. PAC has a high mortality due to its aggressive behavior and resistance to cancer therapeutics. We have shown previously that the proliferation of human PAC cells NCI-H322 and immortalized human small airway epithelial cells HPL1D is stimulated by cyclic adenosine monophosphate (cAMP)/protein kinase A-dependent phosphorylation of cyclic… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS
38 Citations
32 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 32 references

Functional role of beta - adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells

  • A. K. Sood
  • Toxicol . Sci .
  • 2007

Functional expression of metabotropic GABAB receptors in primary cultures of astrocyets from rat cerebral cortex

  • Y. Osawa
  • Biochem . Biophys . Res . Commun .
  • 2006

Functional expression of the GABA receptor in human airway smooth muscle

  • G. N. Wogan
  • Am . J . Physiol . Lung Cell Mol . Physiol .
  • 2006

Similar Papers

Loading similar papers…