• Corpus ID: 32170959

Gamma-Aminobutyric Acid ( GABA ) Introduction

@inproceedings{GammaAminobutyricA,
  title={Gamma-Aminobutyric Acid ( GABA ) Introduction},
  author={}
}
  • Biology

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References

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GABA could work effectively as a natural relaxant and its effects could be seen within 1 hour of its administration to induce relaxation and diminish anxiety and GABA administration could enhance immunity under stress conditions.
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The functional, regional distribution, and pharmacologic properties of various classes of GABAA receptors are summarized and the probable contribution of extrasynaptic GAB AA receptors in the modulation of sleep will be considered.
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Brain Gamma-Aminobutyric Acid Levels Are Decreased in Patients With Phantageusia and Phantosmia Demonstrated by Magnetic Resonance Spectroscopy
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It is indicated that decreased brain GABA levels can serve as biochemical markers of phantageusia and/or phantosmia in patients with these distortions and are the first biochemical changes in the CNS that reflect these sensory changes.
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Adverse events were not observed and an addition of gabapentin into treatment brings improvement of the clinical condition and the presented case reports show a possibility of successful treatment with gabAPentin in severe panic disorders.
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A hypothetical model of altered glutamatergic function in mood disorders is proposed in conjunction with potential antidepressant mechanisms of antiglutamater gic agents, likely to provide new targets for the development of novel antidepressant agents.
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LEG decreased or prevented the epileptic activity, whereas no significant changes were seen with either GABA or phosphatidylserine given alone, suggesting LEG may enhance penetration of GABA across the blood-brain barrier because of the carrier action of the liposomes.
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It is likely that GABA inhibits the first step in the abluminal membrane uptake by brain endothelial cells, and that probenecid selectively inhibits the luminal membrane efflux transport process from the brain capillary endothelial Cells based on the in vivo and in vitro evidence.
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