Gamete-specific epigenetic mechanisms shape genomic imprinting.

  title={Gamete-specific epigenetic mechanisms shape genomic imprinting.},
  author={Pauline Emilie Jullien and Fr{\'e}d{\'e}ric Berger},
  journal={Current opinion in plant biology},
  volume={12 5},
Although most genes are expressed equally from both parental alleles, imprinted genes are differentially expressed depending on their parental origin. In flowering plants, imprinting depends on DNA methylation. Conversely, activation of the expressed allele requires DNA demethylation. This is achieved during female gametogenesis by the synergy between the DNA glycosylase DEMETER and the repression of DNA methylation by the Retinoblastoma pathway. DEMETER is only expressed in the central cell… CONTINUE READING


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