Gallic acid suppresses cell viability, proliferation, invasion and angiogenesis in human glioma cells.

@article{Lu2010GallicAS,
  title={Gallic acid suppresses cell viability, proliferation, invasion and angiogenesis in human glioma cells.},
  author={Yong Lu and Feng Jiang and Hao Jiang and Kalina Wu and Xuguang Zheng and Yizhong Z Cai and Mark Katakowski and Michael Chopp and Shing-shun Tony To},
  journal={European journal of pharmacology},
  year={2010},
  volume={641 2-3},
  pages={102-7}
}
Gallic acid, an organic acid, also known as 3,4,5-trihydroxybenzoic acid, is cytotoxic against certain cancer cells, without harming normal cells. The objective of this study is to evaluate whether gallic acid can inhibit glioma cell viability, proliferation, invasion and reduce glioma cell mediated angiogenesis. Treatment of U87 and U251n glioma cells with gallic acid inhibited cell viability in a dose-dependent manner. BrdU and tube formation assays indicated that gallic acid significantly… CONTINUE READING

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