Gallic acid induces neuronal cell death through activation of c-Jun N-terminal kinase and downregulation of Bcl-2.

@article{Kang2009GallicAI,
  title={Gallic acid induces neuronal cell death through activation of c-Jun N-terminal kinase and downregulation of Bcl-2.},
  author={Min Kyung Kang and Nam Joo Kang and Young Jin Jang and Ki Won Lee and Hyong Joo Lee},
  journal={Annals of the New York Academy of Sciences},
  year={2009},
  volume={1171},
  pages={514-20}
}
Oxidative stress induced by reactive oxygen species (ROS) is strongly associated with the pathogenesis of various neurodegenerative disorders, including Alzheimer's disease. We investigated the possible combined effects of gallic acid and resveratrol, which are major antioxidants present in fruit, including grapes, on PC12 rat pheochromocytoma (PC12) cell… CONTINUE READING