Gallic Acid may have the Potential to Preventing the Development of Preneoplastic Lesions in Liver

@article{RodrguezFragoso2016GallicAM,
  title={Gallic Acid may have the Potential to Preventing the Development of Preneoplastic Lesions in Liver},
  author={L. Rodr{\'i}guez-Fragoso},
  journal={Journal of Liver},
  year={2016},
  volume={5},
  pages={1-1}
}
Figure 1: Microscopic images show the potential chemopreventive effect of gallic acid. Preneoplastic lesions were developed in rats by administration of a single dose of DEN (200 mg/Kg i.p) and CCl4 (2 mL/kg i.p.) during two weeks. Preneoplastic lesions showed the presence of microscopical small-cell dysplastic focus characterized by loss of liver tissue architecture, changes in nuclear morphology, cellular pleomorphism and cell mitosis (arrows). The gallic acid (50 mg/kg p.o.) was given during… Expand

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