Gall-bladder and sphincter of Oddi response to cholecystokinin in the Australian possum.

@article{Iannos1989GallbladderAS,
  title={Gall-bladder and sphincter of Oddi response to cholecystokinin in the Australian possum.},
  author={J. Iannos and G. T. P. Saccone and Michael John Bushell and Robert Andrew. Baker and James Toouli},
  journal={Journal of gastroenterology and hepatology},
  year={1989},
  volume={4 6},
  pages={
          497-503
        }
}
The effects of cholecystokinin octapeptide (CCK-OP) on the gall-bladder (GB) and sphincter of Oddi (SO) of the Australian brush tailed possum were examined in 45 anaesthetized animals. CCK-OP (20-640 ng/kg) consistently caused the GB to contract in a dose-dependent manner (Kruskal Wallis P less than 0.05). In 20 animals, the same dose range of CCK-OP produced an excitatory response in the SO, increasing the SO motility index (MI = frequency of contractions x mean peak amplitude) dose… CONTINUE READING
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