Galenic Preparations of Therapeutic Cannabis sativa Differ in Cannabinoids Concentration: A Quantitative Analysis of Variability and Possible Clinical Implications

@inproceedings{Bettiol2018GalenicPO,
  title={Galenic Preparations of Therapeutic Cannabis sativa Differ in Cannabinoids Concentration: A Quantitative Analysis of Variability and Possible Clinical Implications},
  author={Alessandra Bettiol and Niccol{\`o} Lombardi and Giada Crescioli and Valentina Maggini and Eugenia Gallo and Alessandro Mugelli and Fabio Firenzuoli and Roberto Baronti and Alfredo Vannacci},
  booktitle={Front. Pharmacol.},
  year={2018}
}
Introduction: Magistral preparations of therapeutic cannabis are extracted from standardized products imported from Holland or from the Florence Military Pharmaceutical Chemical Works, but extraction protocols differ among galenic laboratories. This study assessed the inter-laboratory variability in concentrations of cannabidiol (CBD), cannabinol (CBN), tetrahydrocannabinol (THC), and tetrahydrocannabinolic acid (THCA) among different magistral oil preparations. Methods: 219 samples of Bediol… CONTINUE READING

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