Galectins in the Pathogenesis of Rheumatoid Arthritis

  title={Galectins in the Pathogenesis of Rheumatoid Arthritis},
  author={Song Li and Yangsheng Yu and Christopher D Koehn and Zhixin Zhang and Kaihong Su},
  booktitle={Journal of clinical & cellular immunology},
Rheumatoid arthritis (RA) is a complex and common systemic autoimmune disease characterized by synovial inflammation and hyperplasia. Multiple proteins, cells, and pathways have been identified to contribute to the pathogenesis of RA. Galectins are a group of lectins that bind to β-galactoside carbohydrates on the cell surface and in the extracellular matrix. They are expressed in a wide variety of tissues and organs with the highest expression in the immune system. Galectins are potent immune… CONTINUE READING