Galectins as immunoregulators during infectious processes: from microbial invasion to the resolution of the disease.

@article{Rabinovich2005GalectinsAI,
  title={Galectins as immunoregulators during infectious processes: from microbial invasion to the resolution of the disease.},
  author={Gabriel A. Rabinovich and Adriana Gruppi},
  journal={Parasite immunology},
  year={2005},
  volume={27 4},
  pages={
          103-14
        }
}
Recent evidence has implicated galectins, a family of evolutionarily conserved carbohydrate-binding proteins, as regulators of immune cell homeostasis and host-pathogen interactions. Galectins operate at different levels of innate and adaptive immune responses, by modulating cell survival and cell activation or by influencing the Th1/Th2 cytokine balance. Furthermore, galectins may contribute to host-pathogen recognition and may serve as receptors for specific interactions of pathogens with… CONTINUE READING
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