Galectin-induced activation of the transcription factors NFAT and AP-1 in human Jurkat T-lymphocytes.

@article{Walzel2002GalectininducedAO,
  title={Galectin-induced activation of the transcription factors NFAT and AP-1 in human Jurkat T-lymphocytes.},
  author={Hermann Walzel and Matthias Blach and Jun Hirabayashi and Yoichiro Arata and Ken-ichi Kasai and Josef Brock},
  journal={Cellular signalling},
  year={2002},
  volume={14 10},
  pages={861-8}
}
Galectin-mediated ligation of glycoepitopes on T-cell activation markers induces an increase in the cytosolic calcium concentration ([Ca(2+)](i)) originating from a transient Ca(2+) release of internal stores as well as a sustained influx across the plasma membrane. In transiently transfected Jurkat T-lymphocytes, galectins [galectin-1 (gal-1), recombinant human galectin-1 (rec gal-1), nematode 32-kDa galectin (LEC-1), nematode 16-kDa galectin (LEC-6)] differentially stimulate the expression of… CONTINUE READING
16 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…