Galectin-3 is associated with the plasma membrane of lens fiber cells.

@article{Gonen2000Galectin3IA,
  title={Galectin-3 is associated with the plasma membrane of lens fiber cells.},
  author={Tamir Gonen and Paul James Donaldson and Joerg Kistler},
  journal={Investigative ophthalmology & visual science},
  year={2000},
  volume={41 1},
  pages={199-203}
}
PURPOSE To discover proteins that have the potential to contribute to the tight packing of fiber cells in the lens. METHODS Crude fiber cell membranes were isolated from ovine lens cortex. Proteins were separated by two-dimensional gel electrophoresis, and selected protein spots identified by micro-sequencing. The identification of galectin-3 was confirmed by immunoblotting with a specific antibody. The association of galectin-3 with the fiber cell plasma membrane was investigated using… CONTINUE READING