Galectin-3 immunostaining in cytological and histopathological diagnosis of thyroid lesions.

@article{Aiad2008Galectin3II,
  title={Galectin-3 immunostaining in cytological and histopathological diagnosis of thyroid lesions.},
  author={Hayam Abdel Samie Aiad and Mona Abd-Elhalim Kandil and Nancy Yousef Asaad and Ahmad M El-Kased and Sheren F El-Goday},
  journal={Journal of the Egyptian National Cancer Institute},
  year={2008},
  volume={20 1},
  pages={36-46}
}
BACKGROUND Galectin-3 is a human lectin linked to malignant transformation in different organs including thyroid gland. We aimed to evaluate the diagnostic role of galectin-3 in differentiating benign from malignant thyroid lesions in cytological and histological samples. MATERIAL AND METHODS This study included a total of 79 cases; 19 multinodular goiter (MNG), 19 follicular adenoma (FA), 13 follicular carcinoma (FTC) and 28 papillary carcinoma (PTC). Galectin-3 immunostaining was applied on… CONTINUE READING

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