Galectin-3 and metastasis

  title={Galectin-3 and metastasis},
  author={Yukinori Takenaka and Tomoharu Fukumori and Avraham Raz},
  journal={Glycoconjugate Journal},
Galectin-3, a 31 kDa member of the β-galactoside-binding proteins, is an intracellular and extracellular lectin which interacts with intracellular glycoproteins, cell surface molecules and extracellular matrix proteins. Galectin-3 is expressed widely in epithelial and immune cells and its expression is correlated with cancer aggressiveness and metastasis. Galectin-3 is involved in various biological phenomena including cell growth, adhesion, differentiation, angiogenesis and apoptosis. Recent… CONTINUE READING


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