Galectin-3 and PTEN expression in pancreatic ductal adenocarcinoma, pancreatic neuroendocrine neoplasms and gastrointestinal tumors on fine-needle aspiration cytology.

@article{Jiang2014Galectin3AP,
  title={Galectin-3 and PTEN expression in pancreatic ductal adenocarcinoma, pancreatic neuroendocrine neoplasms and gastrointestinal tumors on fine-needle aspiration cytology.},
  author={Kun Jiang and Diane R Lawson and Cynthia K Cohen and Momin T Siddiqui},
  journal={Acta cytologica},
  year={2014},
  volume={58 3},
  pages={281-7}
}
OBJECTIVE Galectin-3 has been implicated in the carcinogenesis of pancreatic ductal adenocarcinoma (PDAC). Its applicability in pancreatic fine-needle aspiration (FNA) in separating malignant from benign lesions has never been addressed. In addition, a correlation between Galectin-3 and tumor suppressor phosphatase and tensin homolog (PTEN) and their potential diagnostic value has never been tested. STUDY DESIGN This study analyzed Galectin-3 immunohistochemical expression in FNA cell blocks… CONTINUE READING