Galectin-1 influences trophoblast immune evasion and emerges as a predictive factor for the outcome of pregnancy.

  title={Galectin-1 influences trophoblast immune evasion and emerges as a predictive factor for the outcome of pregnancy.},
  author={Irene Tirado-Gonz{\'a}lez and Nancy Freitag and Gabriela L Barrientos and Valerie R. Shaikly and Olga Nagaeva and Magnus Strand and Lennart Kjellberg and Burghard F. Klapp and Lucia Mincheva-Nilsson and Marie E Cohen and Sandra Maria Blois},
  journal={Molecular human reproduction},
  volume={19 1},
Galectin-1 (gal-1) is expressed at the feto-maternal interface and plays a role in regulating the maternal immune response against placental alloantigens, contributing to pregnancy maintenance. Both decidua and placenta contribute to gal-1 expression and may be important for the maternal immune regulation. The expression of gal-1 within the placenta is considered relevant to cell-adhesion and invasion of trophoblasts, but the role of gal-1 in the immune evasion machinery exhibited by… CONTINUE READING
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Publications referenced by this paper.
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T cell apoptosis at the maternal-fetal interface in early human pregnancy, involvement of galectin-1.

Proceedings of the National Academy of Sciences of the United States of America • 2008
View 8 Excerpts
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The MAPK signaling cascade.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 1995
View 1 Excerpt
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