Galanthamine production in “shoot-clump” cultures of Narcissus confusus in liquid-shake medium

  title={Galanthamine production in “shoot-clump” cultures of Narcissus confusus in liquid-shake medium},
  author={Salvador Bergo{\~n}{\'o}n and Carles Codina and Jaume Bastida and Francesc Viladomat and Enric Mel{\'e}},
  journal={Plant Cell, Tissue and Organ Culture},
Galanthamine (GAL) is increasingly used in the treatment of Alzheimer's disease. We have attempted to develop a method of producing this alkaloid using in vitro cultures of Narcissus confusus plants. The “shoot-clump” culture in liquid medium was shown to be an appropriate method for the micropropagation of this bulbous plant. The complete process included three steps: 1. culture of “twin-scales” starting from the bulbs; 2. culture of the newly formed shoots in a medium for bud proliferation… CONTINUE READING


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