Galanin receptor subtype GalR2 mediates apoptosis in SH-SY5Y neuroblastoma cells.

Abstract

Recently we have shown that galanin binding significantly correlates with survival in neuroblastoma patients, indicating a possible modulatory role of galanin receptors in neuroblastic tumor biology. However, the molecular mechanisms beyond this correlation have not been elucidated. Here, the cellular effects on activation of specific galanin receptor… (More)

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