Galanin in human pituitary adenomas: frequency and clinical significance.

  title={Galanin in human pituitary adenomas: frequency and clinical significance.},
  author={Betty W Y Leung and Tiina P Iisma and Kin-chuen Leung and Yvonne Janet Hort and Jennifer Turner and John Paul Sheehy and Ken K Y Ho},
  journal={Clinical endocrinology},
  volume={56 3},
OBJECTIVES Galanin (GAL) is a neuropeptide widely expressed in the central and peripheral nervous system and in neuroendocrine tissue, including the adenohypophysis where, in humans, it is expressed in corticotrophs and in ACTH-producing adenomas. Previous analyses of human tissue have used antiserum against porcine GAL for detection of GAL immunoreactivity (GAL-IR) and no pathophysiological correlates have been reported. Given significant differences between the sequence of porcine and human… CONTINUE READING
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