Galactose-specific asialoglycoprotein receptor is involved in lipoprotein (a) catabolism.

  title={Galactose-specific asialoglycoprotein receptor is involved in lipoprotein (a) catabolism.},
  author={Andelko Hrzenjak and Sa{\vs}a Frank and Xingde Wo and Yonggang Zhou and Theo van Berkel and Gert M. Kostner},
  journal={The Biochemical journal},
  volume={376 Pt 3},
Lp(a) [lipoprotein (a)] is a highly atherogenic plasma lipoprotein assembled from low-density lipoprotein and the glycoprotein apolipoprotein (a). The rate of Lp(a) biosynthesis correlates significantly with plasma Lp(a) concentrations, whereas the fractional catabolic rate does not have much influence. So far, little is known about Lp(a) catabolism. To study the site and mode of Lp(a) catabolism, native or sialidase-treated Lp(a) was injected into hedgehogs or ASGPR (asialoglycoprotein… CONTINUE READING
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Identification of megalin/GP330 as a receptor for lipoprotein (a). Arterioscler

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