[Galactose-1-phosphate uridyl transferase and congenital cataract].


The activity of red blood cells galactose-1-p-uridyl transferase (GPUT) was determined by the spectrophotofluorometric method. The average GPUT activity in 102 control subjects was 13. 34 +/- 2. 03u. There were no differences in the sexes and ages. The average GPUT activity in 108 patients with congenital cataract was 11.58 +/- 4. 03u and was lower than that of the controls (P < 0.01). The GPUT activity in 14 of the 108(12.96%)patients was all-3SD below the mean value of the controls (< 7.24u) and the range was from 4.02u to 7.13u with the mean value of 5. 93u being about 44.45% of the normal. The difference between the two groups was statistically significant (P < 0.001). The results indicated that some of the patients with congenital cataract were due to decrease in the GPUT activity. The patients with decrease GPUT activity were mainly suffering from cataracts and their systemic disease were mild.

Cite this paper

@article{Li1991Galactose1phosphateUT, title={[Galactose-1-phosphate uridyl transferase and congenital cataract].}, author={D. Li and Wen-tao Mao and Qiang Ma and Y Chen and Ling Zeng}, journal={Yan ke xue bao = Eye science}, year={1991}, volume={7 2}, pages={67-9} }