Galactomannan detection in computerized tomography-based broncho-alveolar lavage fluid and serum in haematological patients at risk for invasive pulmonary aspergillosis.

@article{Becker2003GalactomannanDI,
  title={Galactomannan detection in computerized tomography-based broncho-alveolar lavage fluid and serum in haematological patients at risk for invasive pulmonary aspergillosis.},
  author={Martin Becker and Elly P J Lugtenburg and Jan J. Cornelissen and Cindy van der Schee and Henk C. Hoogsteden and Siem de Marie},
  journal={British journal of haematology},
  year={2003},
  volume={121 3},
  pages={
          448-57
        }
}
We determined the value of galactomannan (GM) detection in computerized tomography (CT)-based broncho-alveolar lavage (BAL) fluid and serum for the diagnosis of invasive pulmonary aspergillosis (IPA) in haemato-oncological patients with neutropenia. CT of the thorax and BAL were performed systematically at predefined clinical indications. GM was determined by sandwich enzyme-linked immunosorbent assay; the clinicians were unaware of the results. Of 160 patients, 17 patients (10.6%) presented… CONTINUE READING

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