Gait is associated with an increase in tonic firing of the sub-cuneiform nucleus neurons.

@article{Piallat2009GaitIA,
  title={Gait is associated with an increase in tonic firing of the sub-cuneiform nucleus neurons.},
  author={Brigitte Piallat and St{\'e}phan Chabard{\`e}s and Napoleon Torres and Val{\'e}rie Fraix and Laurent Goetz and Eric Seigneuret and Eric Bardinet and Murielle Ursulla Ferraye and Bettina Deb{\^u} and Paul Krack and J{\'e}r{\^o}me Yelnik and Pierre Pollak and A. L. Benabid},
  journal={Neuroscience},
  year={2009},
  volume={158 4},
  pages={1201-5}
}
In animals, the pedunculopontine (PPN) and the sub-cuneiform (SCU) nuclei located in the upper brainstem are involved during the processing of gait. Similar functional nuclei are suspected in humans but their role in gait is unclear. Here we show that, using extra-cellular recordings of the PPN/SCU region obtained in two parkinsonian patients, the SCU neurons increased their firing rate without modifying their firing pattern during mimicked steps. We conclude that SCU neurons are activated… CONTINUE READING