Gaining confidence in high-throughput protein interaction networks

Abstract

Although genome-scale technologies have benefited from statistical measures of data quality, extracting biologically relevant pathways from high-throughput proteomics data remains a challenge. Here we develop a quantitative method for evaluating proteomics data. We present a logistic regression approach that uses statistical and topological descriptors to… (More)
DOI: 10.1038/nbt924

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