Gadolinium-loaded liposomes allow for real-time magnetic resonance imaging of convection-enhanced delivery in the primate brain.

@article{Saito2005GadoliniumloadedLA,
  title={Gadolinium-loaded liposomes allow for real-time magnetic resonance imaging of convection-enhanced delivery in the primate brain.},
  author={Ryuta Saito and Michal T. Krauze and John R. Bringas and Charles O. Noble and Tracy R Mcknight and Pamela A. Jackson and M. Wendland and Christoph Mamot and Daryl C. Drummond and Dimitri B Kirpotin and Keelung Hong and Mitchel S. Berger and John W. Park and Krystof S. Bankiewicz},
  journal={Experimental neurology},
  year={2005},
  volume={196 2},
  pages={381-9}
}
Drug delivery to brain tumors has long posed a major challenge. Convection-enhanced delivery (CED) has been developed as a drug delivery strategy to overcome this difficulty. Ideally, direct visualization of the tissue distribution of drugs infused by CED would assure successful delivery of therapeutic agents to the brain tumor while minimizing exposure of… CONTINUE READING