Gadolinium embedded iron oxide nanoclusters as T1-T2 dual-modal MRI-visible vectors for safe and efficient siRNA delivery.

Abstract

This report illustrates a new strategy of designing a T1-T2 dual-modal magnetic resonance imaging (MRI)-visible vector for siRNA delivery and MRI. Hydrophobic gadolinium embedded iron oxide (GdIO) nanocrystals are self-assembled into nanoclusters in the water phase with the help of stearic acid modified low molecular weight polyethylenimine (stPEI). The… (More)
DOI: 10.1039/c3nr02797j

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@article{Wang2013GadoliniumEI, title={Gadolinium embedded iron oxide nanoclusters as T1-T2 dual-modal MRI-visible vectors for safe and efficient siRNA delivery.}, author={Xiaoyong Wang and Zijian Zhou and Zhiyong Wang and Yunxin Xue and Yun Zeng and Jinhao Gao and Lei Zhu and Xianzhong Zhang and Gang Liu and Xiaoyuan Chen}, journal={Nanoscale}, year={2013}, volume={5 17}, pages={8098-104} }