Gadolinium chloride removes pulmonary intravascular macrophages and curtails the degree of ovine lentivirus-induced lymphoid interstitial pneumonia.

@article{Singh1998GadoliniumCR,
  title={Gadolinium chloride removes pulmonary intravascular macrophages and curtails the degree of ovine lentivirus-induced lymphoid interstitial pneumonia.},
  author={Baneshwar Singh and Andres de la Concha-Bermejillo},
  journal={International journal of experimental pathology},
  year={1998},
  volume={79 3},
  pages={151-62}
}
Ovine lentivirus (OvLV), a retrovirus, causes lymphoid interstitial pneumonia (LIP) in sheep. Pulmonary alveolar macrophages are believed to play a central role in lung inflammation caused by this virus. The pulmonary intravascular macrophage (PIM), a recently identified inflammatory cell, is under active investigation for its role in lung pathology. Gadolinium chloride (GC), a rare earth lanthanide, has been used in in vivo studies to abrogate macrophage function to understand their role in… CONTINUE READING

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