Gadolinium(III) spin labels for high-sensitivity distance measurements in transmembrane helices.

@article{Matalon2013GadoliniumIIISL,
  title={Gadolinium(III) spin labels for high-sensitivity distance measurements in transmembrane helices.},
  author={Erez Matalon and Thomas Huber and Gregor Hagelueken and Bim Graham and Veronica Frydman and Akiva Feintuch and Gottfried Otting and Daniella Goldfarb},
  journal={Angewandte Chemie},
  year={2013},
  volume={52 45},
  pages={
          11831-4
        }
}
Distance determination, by pulse EPR techniques, between two spin labels attached to biomolecules has become an attractive methodology to probe conformations and assemblies of biomolecules in frozen solutions. Among these techniques, double electron-electron resonance (DEER or PELDOR), 5] which can access distances in the range of 1.7 to 8 nm, is highly popular, and the most widely used spin labels are nitroxide radicals. Membrane proteins in their natural environment are of particular interest… CONTINUE READING
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