Gadd45beta is a novel mediator of cardiomyocyte apoptosis induced by ischaemia/hypoxia.

  title={Gadd45beta is a novel mediator of cardiomyocyte apoptosis induced by ischaemia/hypoxia.},
  author={Mi-young Kim and Eun Ji Seo and Dong Ha Lee and Eun Joo Kim and Hye Soo Kim and Hea-Young Cho and Eun Yong Chung and Soo Hwan Lee and Eun Baik and C. H. Moon and Yi-Sook Jung},
  journal={Cardiovascular research},
  volume={87 1},
AIMS Because apoptotic death plays a critical role in cardiomyocyte loss during ischaemic heart injury, a detailed understanding of the mechanisms involved is likely to have a substantial impact on the optimization and development of treatment strategies. The goal of this study was to assess gene profiling during ischaemia/hypoxia and to evaluate the functions of ischaemia/hypoxia-responsive genes in in vivo and in vitro ischaemia/hypoxia-induced cardiomyocyte apoptosis models. METHODS AND… CONTINUE READING


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